The Dose of Innovation Podcast, Episode 1: De-risking Drug Development: The Power of Early-Stage Formulation
Episode 6 of the Health Solutions podcast explores the complex early stages of drug development, highlighting the importance of API solid form, preformulation, and target validation. The episode examines innovative techniques for formulation, the role of Contract Development and Manufacturing Organizations (CDMOs) in accelerating progress, and the advantages and risks of outsourcing. Strategic CDMO partnerships help de-risk projects and speed up the delivery of new medicines.
In This Episode, You Will Learn:
- The “Why” Behind Pre-Formulation: Understand the crucial role of characterizing an API’s physicochemical properties before any development begins.
- Formulation as a De-risking Strategy: Hear how early identification of potential liabilities saves invaluable time and resources down the line.
- Connecting the Lab to the Clinic: Learn how the right formulation directly impacts a drug’s bioavailability and, therefore, its therapeutic success.
- Navigating Excipient Selection: Gain insights into the art and science of choosing the right inactive ingredients to ensure your drug product is stable, manufacturable, and effective.
- Real-World Application: Listen to our scientists discuss anonymized case studies where expert formulation overcame significant development hurdles.
Meet Our Experts
This episode features a deep-dive conversation with senior scientists from the iHealth Solutions Pharmaceutical R&D laboratory. With decades of combined experience, they provide practical insights and expert commentary on overcoming today’s most complex formulation challenges.